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Biology Lead
Posted on Dec. 19, 2024
- Bundoora, Australia
- 0 - 0 USD (yearly)
- Full Time

- Responsible for the design and execution of the biology research programs across multiple preclinical programs, ensuring alignment with overall company goals and strategy.
- Lead and mentor staff to carry out the biology research program and provide leadership to project teams through a matrix structure.
- Play a key role in developing and advancing ACTT’s vision and strategy by driving the target selection process, working closely with other members of the ACTT Executive to prioritise high-impact programs based on unmet medical needs, market differentiation, published scientific and clinical data, relevance of animal models and clinical trial feasibility.
- Identify and manage relationships with third parties including academic partners, clinicians and consumers in specified disease areas.
- Develop preliminary target product profiles and help align preclinical research and development activities to the clinical endpoint.
- Oversee and ensure the successful execution of in vitro and in vivo studies to support lead discovery and optimisation.
- Ensure robust preclinical development programs, including biomarker identification and validation, ADME/PK, DMPK and toxicology studies to support IND filings.
- Stay abreast of emerging trends and technologies in the field of drug discovery and biology, ensuring that the company maintains cutting-edge capabilities in target biology, assay development, and disease modelling.
- Work closely with other stream leads to align research activities with company objectives, manage project resources, budgets and timelines.
- Communicate findings and strategic goals to the executive team, board members and external stakeholders, including partners and investors.
- Provide guidance, training, and mentorship to staff to foster professional growth and development.
- Education: PhD in Biology or a relevant field
- 5+ years of experience in drug discovery and development, with at least 2 years in a leadership role.
- Proven track record in leading and advancing preclinical biology research in a drug development environment.
- Strong expertise in cell biology, molecular biology, biochemistry, and in vivo disease models, with protein degrader experience highly desirable.
- Experience with small molecules is highly desirable
- Demonstrated ability to build, lead, and inspire teams.
- Strong project management and organisational skills with a history of successfully advancing drug candidates through the development pipeline.
- Broad knowledge of relevant disease areas and mechanisms of action for therapeutic intervention.
- Familiarity with cutting-edge research techniques, including CRISPR, gene editing, and high-throughput screening technologies.
- Excellent written and verbal communication skills, with the ability to communicate complex scientific ideas clearly to diverse audiences, including the executive team, Board members and external stakeholders.
- Deep understanding of the drug development process, including regulatory requirements and preclinical models in an industry setting.
- Highly collaborative, able to work across diverse teams in a matrix organisation to achieve common goals.
- Strong problem-solving skills, with a pragmatic and solutions-oriented approach.
- Strong project and time management skills to lead multiple tasks and projects simultaneously with varying timeframes and within budget
This position is available for a fixed term until 30 Mar 2026 in a full-time capacity. Salary is Research Employee Level C1-C6 ($139,851 – $161,255). Up to 17% superannuation and very attractive salary packaging options are available Location is the WEHI Biotech Centre, Bundoora
Please apply by uploading your CV, cover letter and a document addressing the key selection criteria outlined in the Job Description in pdf format.
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