Technician To Study The Mechanisms Of Kidney Disease

1 year with the possibility of a 1-year extension The Kidney Physiology group at the Radboudumc aims to decipher the pathophysiological mechanisms of ion transport disorders. By identification of genes involved in kidney tubulopathies, we aim to increase our understanding of the molecular mechanisms of ion reabsorption in the kidney. You will contribute to our research by performing laboratory work. Are you the technician to join us? We would like to get to know you!

Embedded in the department of Medical BioSceinces of Radboudumc, we study the regulation of ion transport by the kidney, as well as, the role of minerals in diabetes mellitus type 2 and chronic kidney disease.

The development of next-generation diagnostics and innovative functional methods to measure ion transport are essential to diagnose and to understand kidney tubulopathies. We envision that patient-specific models are the future of pathophysiological research. Personalized drug screening to identify therapeutics that fit the needs of individual patients will become the new standard for treatment of rare diseases.

You will be responsible for performing the most common laboratory work in kidney physiology. Your main tasks will include:

• Molecular biology (e.g. Construction of DNA plasmids).
• Culture and transfection of various mammalian cell lines.
• Biochemical techniques (e.g. Western Blot, Protein Precipitation).
• Immunohistochemistry.
• Implementation of new techniques and supporting existing projects.

At Radboud university medical center, you build on your future. We are committed to providing the best care, education, and research. And we are true to our word, because we help you develop and seize opportunities and give you the room to grow. As an employer, we believe that employees should feel vital and happy at work in all stages of life. We are also committed to creating a healthy and safe working environment. Our employment conditions contribute to that. What we offer:

• A gross monthly salary between € 3.330 and € 4.429 (scale 8) for full-time employment (36 hours per week). You will also receive an 8% holiday allowance, an 8.3% end-of-year bonus, and, depending on the position, an allowance of 47% to 72% for working irregular hours.
• 172 vacation hours per year based on a 36-hour working week. (As of 1 January 2025, you will receive 176 vacation hours).

The department of Medical BioSciences provides an international and stimulating working environment and is an exciting place to perform translational and clinical research and enjoy teaching. The department has complementary research groups whose interests range from cardiovascular disease, molecular regulation of ion transport processes in the kidney to the study of metabolism in the body. Working collaboratively within the department, we use our expertise to investigate how molecules, cells, organisms and humans function and how we might modulate their physiology to ultimately improve health of kidney patients. This project will be executed in the Kidney Physiology group, which is part of the 3D Biology and Kidney Disorders Research Programs within the Radboudumc.

Radboudumc
Welcome to Radboud university medical center (Radboudumc), where our research groups strive for innovative solutions that make impact on health and healthcare. We challenge the status quo to overcome current and future health challenges. Our goal is to shape the future of healthcare for generations to come. Our focus is on prevention, sustainability, and meaningful care, which we achieve through our in-depth understanding of disease mechanisms, clinical science, public health research, medical technology and data science. Our approach is centered on breakthroughs that can truly enhance personalized healthcare and public health.

At Radboudumc, a comprehensive range of research programs provide the compass for our research efforts. Each program has a clear goal, where collaboration within and outside our organization is highly valued. We integrate care, education and research in partnership with our patients to ensure that our research programs have significant impact on health and healthcare. We invite you to join us in our mission to create a healthy future for all. You have completed a studie at hbo level in Biology, Life Sciences or Laboratory research and experience with basic molecular and cellular lab techniques. Your working style is independent and well-structured. Further you posses well-developed social skills directed to work in a team and a flexible working attitude. You are proficient in English. Any questions? Or wondering what it is like to work at Radboudumc? Then call or email to Dr. Jeroen de Baaij, +31 (0) 24 361 05 80. Use the Apply button to submit your application.

Applicants should send a letter of intent outlining special interest in the position, overall related qualifications, experience and career goals, a curriculum vitae and names and addresses of professional references.